Biomedical researchers suspect graphene, a novel nanomaterial made of sheets of single carbon atoms, would be useful in a variety of applications. But no one had studied the interaction between graphene and DNA, the building block of all living things. To learn more, PNNL's Zhiwen Tang, Yuehe Lin and colleagues from both PNNL and Princeton University built nanostructures of graphene and DNA. They attached a fluorescent molecule to the DNA to track the interaction. Tests showed that the fluorescence dimmed significantly when single-stranded DNA rested on graphene, but that double-stranded DNA only darkened slightly – an indication that single-stranded DNA had a stronger interaction with graphene than its double-stranded cousin.
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